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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SYS1 All Species: 34.85
Human Site: S43 Identified Species: 69.7
UniProt: Q8N2H4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N2H4 NP_291020.1 156 17615 S43 L V D G L V R S S P S L D Q M
Chimpanzee Pan troglodytes XP_514675 276 30313 S163 L V D G L V R S S P S L D Q M
Rhesus Macaque Macaca mulatta XP_001109290 252 27995 S139 L V D G L V R S S P S L D Q M
Dog Lupus familis XP_543018 152 17075 S43 L V D G L V R S S P S L D Q M
Cat Felis silvestris
Mouse Mus musculus Q78S06 156 17535 S43 L V D A L V R S S P S L D Q M
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508808 264 29018 S151 L V D S L V Q S S P S L D Q M
Chicken Gallus gallus XP_417361 156 17398 T43 L L G A L G S T G P S L H Q I
Frog Xenopus laevis NP_001079422 156 17940 Y43 A L D L V V H Y S P S L D Q I
Zebra Danio Brachydanio rerio XP_001918846 156 17784 T43 G V D G L V Q T S R S L D Q I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649809 160 18270 D44 V A N K L S G D N Y S L D H L
Honey Bee Apis mellifera XP_001120649 160 18473 S46 I V A S Y I G S T K S L D Y V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796556 155 17604 H43 F V D Y I L D H P R S L G Q I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 55.7 61.9 80.1 N.A. 97.4 N.A. N.A. 54.1 79.4 75 73.7 N.A. 43.7 43.1 N.A. 51.9
Protein Similarity: 100 56.5 61.9 83.9 N.A. 98.7 N.A. N.A. 56.8 86.5 87.1 87.1 N.A. 63.7 65.6 N.A. 69.8
P-Site Identity: 100 100 100 100 N.A. 93.3 N.A. N.A. 86.6 40 53.3 66.6 N.A. 26.6 33.3 N.A. 33.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 N.A. N.A. 93.3 60 73.3 86.6 N.A. 53.3 60 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 9 17 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 75 0 0 0 9 9 0 0 0 0 84 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 9 42 0 9 17 0 9 0 0 0 9 0 0 % G
% His: 0 0 0 0 0 0 9 9 0 0 0 0 9 9 0 % H
% Ile: 9 0 0 0 9 9 0 0 0 0 0 0 0 0 34 % I
% Lys: 0 0 0 9 0 0 0 0 0 9 0 0 0 0 0 % K
% Leu: 59 17 0 9 75 9 0 0 0 0 0 100 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 50 % M
% Asn: 0 0 9 0 0 0 0 0 9 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 9 67 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 17 0 0 0 0 0 0 84 0 % Q
% Arg: 0 0 0 0 0 0 42 0 0 17 0 0 0 0 0 % R
% Ser: 0 0 0 17 0 9 9 59 67 0 100 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 17 9 0 0 0 0 0 0 % T
% Val: 9 75 0 0 9 67 0 0 0 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 9 0 0 9 0 9 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _